Discover Your Ideal Santa Fe, Medellin Antioquia Vacation Rentals for a Memorable Colombian Getaway
Discover Your Perfect Santa Fe Vacation Homes
Best Vacation Homes in Santa Fe
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Santa Fe Luxury Rentals
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Santa Fe Pet Friendly Vacation Rentals
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Santa Fe Large Vacation Homes
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Why Choose Rent By Owner for your Santa Fe Vacation Rental Homes?
What makes our Vacation Rentals special?
Popular Areas for Santa Fe Vacation Rentals
Where are the best neighborhoods to stay in Santa Fe?
When exploring Santa Fe in Medellin, Antioquia, Colombia, choosing the right neighborhood can enhance your travel experience. Whether you prefer the vibrant atmosphere of the city center or a more relaxed setting, each area offers unique charm and convenience. From trendy districts with local cafes to serene residential neighborhoods, you'll find options that suit your preferences for comfortable and accessible vacation rentals. By selecting the ideal neighborhood in Medellin, you ensure your stay is both enjoyable and memorable, making your visit to Colombia truly exceptional.
Perpetuo Socorro
This tranquil neighborhood offers a peaceful retreat while still providing easy access to the vibrant city life of Medellin. Here, you can enjoy comfortable vacation rentals that blend seamlessly with the area's relaxed atmosphere, making it an ideal choice for a restful stay in Antioquia.
View 1244+ Rentals in Perpetuo SocorroBest Times to Visit Santa Fe
When should you plan your Vacation Rentals stay?
To make the most of your stay, consider visiting during the region’s optimal seasons when the weather enhances your experience in Santa Fe, Medellin, Antioquia, Colombia, ensuring you select the right time to enjoy all that this destination has to offer.
Peak Season Highlights
December to February
During the winter months, this area experiences peak tourism as travelers seek to enjoy the warm climate and festive atmosphere, making it a lively time to book your vacation rental.
June to August
The summer months attract many visitors who want to experience the region’s vibrant culture and outdoor activities, leading to increased demand for vacation rentals.
Off-Season Highlights
March to May
Spring offers a quieter period with fewer visitors, providing a more relaxed environment to enjoy your stay while still experiencing pleasant weather conditions.
September to November
Fall sees a lull in tourist activity, making it an ideal time to find more affordable and tranquil vacation rentals in this destination.
Weekly Weather Forecast for Santa Fe
How to Book Your Santa Fe Vacation Rental Home
What's our booking process?
Booking Steps
Search Properties
Select a Rental
Book Online
Explore and book the perfect rental in Santa Fe
Common Vacation Rentals Amenities
What amenities can you expect?
Indoor Features
- Fully-equipped kitchens with modern appliances
- Comfortable living areas with flat-screen TVs
- Free Wi-Fi for staying connected
- Air conditioning and heating for year-round comfort
- In-unit washers and dryers for convenience
- Luxurious bedrooms with premium bedding
- Spa-like bathrooms with soaking tubs or walk-in showers
Outdoor Amenities
- Enjoy a private outdoor patio or balcony to relax and take in the scenic views of the region.
- Take advantage of the lush gardens and landscaped outdoor spaces available at many properties.
- Make use of communal swimming pools that offer a refreshing way to unwind after exploring the area.
- Benefit from on-site BBQ grills or outdoor dining areas perfect for entertaining family and friends.
- Experience the convenience of outdoor parking facilities, ensuring easy access during your stay.
- Engage in outdoor recreational activities such as walking or jogging paths within the property grounds.
- Utilize outdoor terraces or rooftop decks that provide panoramic views of the surrounding landscape.
Top Attractions Around Santa Fe
What attractions are nearby?
In this vibrant region, you'll find a variety of activities nearby, from exploring local cultural sites to enjoying outdoor adventures that showcase the area's natural beauty and lively atmosphere.

Family Activities
- Exploring the Santa Fe Art Market: Discover vibrant local art and craftsmanship, offering a family-friendly cultural experience in a lively setting within this scenic region.
- Guided Nature Walks: Enjoy educational guided hikes through Santa Fe’s lush trails, ideal for engaging children with the area's diverse flora and fauna.
- Santa Fe Children's Museum: Spend quality time at an interactive museum designed to inspire creativity and learning for young visitors exploring here.
- Historic Plaza Tours: Take a family stroll around the historic city center, soaking in the rich history and captivating architecture that define this destination’s charm.
Adult Activities
- Old Town Santa Fe Tours: Explore the historic district on guided walking tours that highlight its unique adobe architecture and vibrant art scene.
- Skiing in the Area: During winter months, hit the nearby slopes to enjoy skiing and snowboarding adventures that showcase the region’s snowy landscape.
- Culinary Experiences: Indulge in local flavors through gourmet dining experiences and cooking classes in the charming streets of Santa Fe.
- Art Galleries and Studios: Visit renowned galleries and artist studios to immerse yourself in the area's rich cultural and creative heritage.
- Mediterranean Nature Hikes: Discover scenic trails and lush landscapes while enjoying the peaceful natural beauty that defines this part of Medellín.
- Metropolitan Cable Car Rides: Take advantage of the modern cable cars for panoramic views over the city and surrounding mountains.
- Cultural Festivals and Events: Attend lively festivals celebrating Antioquia’s traditions, music, and local artisans throughout the year.
- Nightlife and Dining: Experience vibrant nightlife with trendy bars and restaurants offering authentic Colombian cuisine in the city center.
Other Places to Stay in Santa Fe
Santa Fe Travel Tips
How Can You Make the Most of Your Stay?
- Explore local art and culture: Take advantage of the vibrant arts scene in this destination by visiting galleries and workshops to gain a deeper understanding of the region’s creative spirit.
- Savor regional cuisine: Indulge in authentic flavors at local eateries, which offer a taste of the area's unique culinary traditions right within your stay.
- Use public transportation or walk: Navigate the area easily and immerse yourself in the local atmosphere by opting for walking tours or reliable transport options around your accommodations.
- Plan outdoor excursions: Make the most of the region’s natural beauty by scheduling nearby outdoor activities that complement your relaxing stay in these vacation rentals.
Transportation Options
- Metro Medellin:** The metro system provides a quick and affordable way to navigate the city and explore local attractions from your vacation rental.
- Tuk-tuks:** These colorful, three-wheeled vehicles offer an authentic, flexible transport option for short trips around the area.
- Taxis and Ride-Sharing Services:** Reliable taxis and popular ride-sharing apps like Uber ensure comfortable journeys between your rental and key destinations.
- Private Car Rentals:** Renting a car offers you the freedom to discover the region at your own pace, especially if you're planning to visit outskirts or scenic spots.
Local Customs Options
- Respect for Religious Traditions: Many local religious festivals and processions are integral to the area's cultural fabric, and participating respectfully is highly valued.
- Greeting Etiquette: A warm handshake or a friendly nod accompanied by eye contact is customary when greeting locals in this destination.
- Dining Customs: It is polite to wait for a toast or the host to begin eating before you start, especially during traditional meals.
- Celebration of Local Festivals: Participating in community festivals and events offers an authentic experience of the region’s vibrant cultural customs.
Frequently Asked Questions About Santa Fe?
1. What are the top vacation rentals in Santa Fe?
There are a lot of options in Santa Fe. If you plan on staying in the Santa Fe area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Santa Fe:
- Luxurious Apartment Suite that offers a dream stay & complete comfort
- Casa del Reloj CIELO -Luxury, Jacuzzi, Penthouse Suite, 4000sq Feet, to 200mbps
- 8 BR Luxury 6000 S.F. Mansion , 2 Bars Hot Tub, Bbq and Ac
- Casa del Reloj CASCADA -Luxury, WaterFall Jacuzzi, Apartment Suite, 1130 sq Feet
- 10BRPOBLADOMANSIONPOOLJAVUZZIPRIVATE
- Luxury Apartment with A/C at Energy Living - El Poblado n
- Parque Lleras Luxury 4br apartment
- Alojamiento en Medellín
- The Somos Loho Hotel
- Excepcional Casa Privada para Familias y Grupos - Excelente Ubicación
2. How many vacation rentals have private pools in Santa Fe?
There are 127 vacation rentals with private pools near Santa Fe. Top-rated RBO homes that have access to a swimming pool include:
3. Which vacation homes in Santa Fe are best for families?
If you are looking for a family-friendly vacation home in Santa Fe, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Santa Fe:
4. How many Rentbyowner vacation rentals are available in Santa Fe?
Currently, the total number of properties listed by Rent By Owner in 2025 is over 6324 in the Santa Fe area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Santa Fe.
5. What is the cancellation policy for properties in Santa Fe or Medellin?
6. How do I confirm my booking at a vacation rental in this area?
7. Are there any house rules or restrictions I should be aware of before booking?
8. What amenities are generally available in vacation rentals here?
9. How do I handle questions or special requests when booking a vacation rental in this region?
Santa Fe Top Rated Vacation Rentals
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- View
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